Telomere Length and Neighborhood Circumstances: Evaluating Biological Response to Unfavorable Exposures
نویسندگان
چکیده
منابع مشابه
Biological Response to Spe Exposures
It has long been recognized that a single solar particle event (SPE) can produce, over a short period of time, exposures on the order of LD50 for humans under normal physiological conditions. It is further recognized that recovery from injury over the period of exposure would greatly increase the chances of survival (dose rate effects) although such effects were left unquantified. In the presen...
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Telomeres, the TTAGGG tandem repeats at the ends of chromosomes, become progressively shortened with each replication of cultured human somatic cells (reviewed in Wong and Collins (Wong & Collins 2003)) until a critical length is achieved, at which point the cell enters replicative senescence. This situation can be reversed by the enzyme named telomerase that is responsible for Telomere Length ...
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ژورنال
عنوان ژورنال: Cancer Epidemiology Biomarkers & Prevention
سال: 2017
ISSN: 1055-9965,1538-7755
DOI: 10.1158/1055-9965.epi-16-0554